The mGluR8 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GRM8. This antibody recognizes Human, Mouse, and Rat antigen. The mGluR8 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Description: mGluR8 Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. Belongs to the G-protein coupled receptor 3 family. Interacts with PICK1. 3 isoforms of the human protein are produced by alternative splicing.
Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Subunit Structure: Interacts with PICK1.
Similarity: Belongs to the G-protein coupled receptor 3 family